Levomethorphan is the enantiomer of dextromethorphan. In contrast to DXM which is a dissociative and antitussive, levomethorphan is an opioid analgesic. Levomethorphan is metabolized by cytochrome P450 enzymes 2D6 and 3A4, the same liver enzymes that are used to metabolize DXM. It is a potent opioid analgesic approximately five times stronger than morphine but less potent than levorphanol as it must be demethylated by liver enzymes before becoming active. [1]

^ Hindmarch, Ian. "The enantiomer debate: current status and future directions." Human Psychopharmacology: Clinical and Experimental. 16.S2 (Dec 2001): S101 - S104. http://dx.doi.org/10.1002/hup.338

Created by viscosity, 05-19-2010 at 01:15 PM Last edited by viscosity, 07-22-2010 at 04:42 PM 0 Comments, 384 Views